1.    What is varicocele?

Varicoceles represent abnormal enlargements of blood vessels within the scrotum, akin to enlarged veins in the legs. The pampiniform plexus, in the spermatic cord, is responsible for the drainage of blood from the testes. Varicoceles generally develop upon entering puberty, and anatomical differences reveal that they occur more frequently on the left. While many are asymptomatic, varicoceles cause such pains as discomfort, shrinkage of the testes, and infertility issues by compromising sperm production and quality. The condition is prevalent and occurs in about 15% of males. Varicocele is one of the leading causes of treatable male infertility. Surgical intervention is seldom proposed; other treatment methods may be recommended.

2.    Which is the common side for Varicocele?

Varicoceles usually occur on the left-side of the scrotum, with studies reporting that nearly 90% of the cases involve the left testicle. This may be due to anatomical differences, with the left testicular vein draining into the left renal vein at a right angle, effectively raising resistance to blood flow, thereby causing pooling. Further, the left side also has comparatively less efficient valves in its venous system, giving it a greater propensity for blood pooling. Though rarer, varicoceles may occur on the right side or both. Identifying whether the varicocele is unilateral or bilateral and of what grade is very helpful in making a diagnosis, since left-sided varicoceles also have a greater effect on fertility.

3.    What is the main cause of varicocele?

The main causative factor for varicocele includes defective valves in the veins of the spermatic cord, which set an automatic deflection to the proper flow of blood. The venous blood accumulates, not draining away properly; hence, the veins start dilating and produce a varicocele. Reevaluation of the left renal venal status, anatomical difference, and genetic disposition contribute to varicocele; it can raise scrotal temperature and impair testicular function and influence sperm production. The exact causes are not always discernible. Varicoceles are usually not caused by trauma or infection. Knowledge of the original cause helps in achieving successful treatment.

Risk factors for developing varicocele:

  • Age: The onset is most common during puberty, mainly because of rapid growth and changes in blood flow patterns.
  • Anatomical Differences: A longer left testicular vein that drains into the left renal vein at a right angle increases susceptibility.
  • Genetic Predisposition: Family history of varicose veins or venous insufficiency increases the risks.
  • Increased Abdominal Pressure: Heavy lifting, straining, or chronic constipation.
  • Body Type: It seems there would be a greater risk of this in tall or thin individuals due to different structure and pressure dynamics of the veins.
  • Lifestyle Factors: Prolonged standing or heavy lifting can strain the abdominal area.
  • Underlying Conditions: Rarely, tumors or other conditions that compress the venous system may lead to varicocele formation.

Being aware of these factors could direct one toward early detection, thus timely management.

4.    Is a varicocele hereditary?

Varicoceles are not directly inherited; however, the cause continues to be genetic in a wide sense. A person with a family background of problems concerning vein health would be more possible to develop a varicocele, revealing an innate capacity that exists that weakens veins or any morphological defect in such. Still, other factors such as anatomical differences and increased abdominal pressure play a significant part in the development of varicocele.

5.    How is Varicocele Infertility Caused?

• Temperature of the Testes

A varicocele causes the temperature of the scrotum to be raised by restricting the ambient blood flow which impairs the cooling of the testes. High temperatures are known to depress spermatogenesis, which leads to decrease in the number and quality of sperm. Over time and if untreated, this thermal imbalance can impair testicular function and therefore cause infertility.

• DNA Abnormalities of the Sperm

An increase in oxidative stress and reactive oxygen species (ROS) occurs within the testicular environment in the presence of varicocele. This causes oxidative damage and subsequently compromises the integrity of sperm DNA, leading to a decrease in fertility either through impairment of fertilization, increases in the risk of miscarriage, or increases in the risk of genetic abnormalities.

·      Lowered testosterone levels

Varicoceles obscure the blood flow and oxygen delivery to the testes, leading to an uneasy work of endocrine functions within them. It causes lowered testosterone levels, which are necessary for sperm production, libido, and general reproductive health, thus playing an indirect role in infertility among them.

·      Reduced semen quality

Varicoceles affect the production and quality of semen by damaging the testicular environment. This results in lower sperm count, reduced motility, and abnormal morphology, which together significantly decrease the chances of natural conception.

·      Varicocele Symptoms

Aspiring from varicoceles are symptoms that may include discomfort, swelling, or recognizable mass contained within the scrotum. Some emerge manually when there is underlying testicular dysfunction leading to long-term problems affecting sperm output, testicular health, and hormonal balance affecting fertility.

Recognize These Early Warning Signs:

·      Painless testicular lump

A painless enlargement on the testicular structure can emanate from a varicocele, implying that one of the veins has dilated. It is often described as “bag of worms” and usually expands when standing or straining. In preventive medicine, varicocele detection should be attended with utmost care so that other complications, including those relating to infertility, do not arise.

·      Reduced sperm count

Varicoceles can impair spermatogenesis by disrupting testicular temperature and blood flow, leading to a significant reduction in sperm count. This decline often becomes noticeable during fertility evaluations and is a key indicator of varicocele-related infertility.

·      Reduced sperm motility

Varicoceles interfere with normal blood flow and induce oxidative stress, resulting in cell damage that reduces sperm motility. The motility of sperm is profoundly important for travel and fertilization of the egg; therefore, reduced motility lowers the chances of conception.

·      Chronic testicular pain

Chronic pain, ranging from dull to sharp, might indicate the development of a varicocele. The discomfort often worsens with long periods of standing or physical activity and should attract medical attention.

·      Testicle discomfort on a particular side

Varicoceles occur more commonly on one side—almost invariably the left side. If discomfort or swelling occurs on this side, it may indicate increased venous pressure, suggesting the early formation of a varicocele with possible testicular dysfunction.

• Dilated veins that can be felt in the scrotum

The enlargement of veins, which often can be palpated as a soft mass in the scrotum, is the hallmark of varicocele. These veins may become prominent with standing or straining and need physical evaluation for confirmation.

• Heaviness or dragging sensation in the scrotum

A dragging or heavy feeling in the scrotum may signify a pooling of blood in dilated veins. Such a symptom often accompanies varicocele and can indicate a compromised function of the testes needing intervention.

• Complications Associated       

1. Oligospermia

Oligospermia, low sperm count, is a most common complication of varicoceles. This compromised blood flow and increased temperature in the scrotum disrupt sperm production, resulting in fewer viable sperm. It thus significantly reduces fertility and renders a couple’s conception almost impossible without medical intervention, such as varicocele repair or assisted reproductive techniques.

2. Hydrocele

Hydrocele is fluid accumulation in the scrotum that may arise due to varicocele or its surgery. This fluid causes swelling and discomfort in the scrotum, which may interfere with testicular function. Hydrocele is generally painless, but, in severe cases, drainage or corrective surgery may be needed.

Physical Examination

• USG Scrotum Test


Scrotal ultrasound (USG) is a powerful diagnostic tool for varicocele. It employs sound waves to create images of the scrotum, enabling the physician to assess the vein’s sizes, blood flow, and extent of venous dilation. This non-invasive diagnostic investigation can confirm the diagnosis and stage the varicocele.

·      Valsalva Manoeuvre

The Valsalva maneuver consists of having patients bear down or hold their breath for increasing abdominal pressure. This technique improves the visibility of dilated veins during physical examination or ultrasound, thus making it easier to identify varicoceles. It is a simple and effective diagnostic maneuver often performed in a clinical setting.

• Scrotal Doppler Ultrasound

The scrotal Doppler ultrasound measures the blood flow within the scrotum and the veins of the pampiniform plexus. It can identify abnormal blood reflux, vein dilation, and the severity of the varicocele. This advanced imaging examination is crucial for confirming the diagnosis of varicocele and determining treatment options.

6. Does Varicocele Affect Fertility?

A varicocele is the engorgement of the veins in the scrotum, just like varicose veins. Such dilated veins corrupt the normal flow of blood from the testes, which may cause impairment of testicular function leading to discomfort, testicular shrinkage, and ultimately infertility if not treated.

Varicocele surgeries:

·      Open surgery

Open surgery or varicocelectomy involves creating an incision either in the groin or in the lower abdomen to access and tie off the inflamed vein. This is the conventional form, with good success, and is done under local or general anesthesia with an aim to minimize the effect of blood pooling and returning normal blood flow. Recovery from the surgery requires about two or three weeks.

·      Laparoscopic Surgery

This method uses capacitive control technology and enclosed instruments through which a camera can aid in tying the dilated vein. The recovery is quicker and slightly less painful than the open surgical procedure. Under general anesthesia, all techniques used in the surgical treatment of larger or recurrent varicoceles are considered efficacious.

·      Microsurgical Varicocele

Microsurgical techniques use a high-powered surgical microscope to analyze the veins, identify which ones need to be tied off, and repair them. The procedure minimizes damage to surrounding structures such as lymphatics and arteries, thus reducing the chances of developing complications such as hydrocele. This method offers the higher success rate and quicker recovery.

·      Percutaneous embolization

Percutaneous embolization is a non-surgical and minimally invasive procedure in which a catheter is guided to the affected veins to seal them with the use of coils or a sclerosing agent. Surgery is done under local anesthetic, has very little recovery downtime, and offers a viable option for patients who would prefer to avoid surgical methods entirely.

Complications of varicocele surgery:

  • Fluid surrounding the testicle that may result in swelling.
  • Varicocele may reappear if not completely closed.
  • A very rare cause is shrinkage of the testicle due to damage to artery systems.
  • May occur in the region of the operation or at the point of catheter insertion.
  • Major bleeding or obvious scaring after the operation.
  • Persistent discomfort after the procedure.
  • Rare injury to arteries, veins, or lymphatics.
  • Complications arising from anesthetics, whether general or local.

7.    Is it necessary to have surgery for varicocele?

Varicocele surgery is seldom needed unless it causes severe symptoms, namely chronic pain, shrinkage of the testicle, and infertility. As per mild asymptomatic cases, treatment is unnecessary and these cases would be followed up.

8.    Can varicocele be cured naturally?

Cure of varicocele requires no popular home remedy. It has become a challenge in an examination driving treatment or therapy considering that there are a few and very rarely effective. Strong support of the scrotum with firm, elastic, and supportive underwear can reduce the discomfort. While a few home remedies may alleviate pain, they cannot eradicate the condition; this requires treatment for a lasting cure.

Varicocele treatment without surgery

·      Lifestyle Modifications

Wear supportive underwear to relieve discomfort.

Avoidance of heavy lifting and all activities that may increase abdominal pressure.

Keeping body weight within normal limits has reduced the strain on abdominal veins.

·      Pain Management

Over-the-counter medications such as ibuprofen or acetaminophen can be effective in relieving mild pain caused by the varicoceles.

·      Regular Monitoring

In asymptomatic or mild cases of the condition, usual check-ups and ultrasounds can be routinely done to monitor the condition with no intervention.

Why to choose Dr Ankit Kayal for Microscopic Varicocelectomy surgery for varicocele Treatment ?

Ankit Kayal is a well-trained urologist and known to be one of the most skilled microscopic varicocelectomy surgeons. He is reputed to have an expeditious recovery with few complications and excellent results for the patient as a result of his wealth of experiences. Working with the use of high ocular magnifications to identify small veins, microsurgery enables him to repair veins reliably while preserving the surrounding structures such as arteries and lymphatics. In addition, Dr. Kayal has a patient-centered approach to delivering customized treatment plans that address the resolution of infertility and symptom relief. With high standards established while maintaining a cutting-edge approach, he provides patients with the highest standard of care, earning the trust of patients for varicocele treatment and high success rate.

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FAQs on Varicocele

1.    What is varicocele?

A varicocele is yet another cause of conditions that lead to testicular unrest. The easy way of describing varicocele is that it is an abnormal enlargement of veins within the scrotum, much like varicose veins outside the body. These dilated veins disrupt the normal blood flow from the testes, treating discomfort, testicular shrinkage, and fertility problems if untreated.

Where does varicocele occur?

Any varicocele in the scrotum entirely occurs in the pampiniform plexus veins that drain the testes; this condition is quite common on the left side due to some anatomical variations concerning venous drainage.

Are varicoceles common?

The yes response is usually qualified by the statement that varicoceles are common and, therefore, found in approximately 15% of boys. Varicoceles are commonest during puberty and are amongst the leading causes in treatable male infertility, particularly for men that have reproductive challenges.

What are the symptoms of varicoceles?

Dull ache, weight, or swelling in the scrotum, prominent or bulging veins that may be palpable, and in some instances testicular shrinkage are symptoms. Many are covert, discovered during fertility evaluation or routine examinations.

What causes varicoceles?

Varicoceles arise due to defective valves in the veins of the spermatic cord, resulting in blood pooling and dilating the vein. Anatomical changes, increased abdominal pressure, and genetic predisposition can all contribute toward their causation.